We work with key partners to advance our understanding of how the CNS will impact and be effected by cure strategies. Projects are managed by a leadership team comprised of Principal Investigators at the U.S. Military HIV Research Program and Yale University.
Leadership
Serena Spudich, MD
Dr. Spudich is a neurologist whose clinical and translational research is focused on the pathogenesis of HIV in the nervous system, in particular the impact of acute HIV infection and early treatment on the central nervous system and the establishment of persistent CNS reservoirs for HIV. Dr. Spudich graduated from medical school at the University of California, San Francisco in 1997, then pursued residency training at the University of Washington in Internal Medicine and at the Massachusetts General Hospital/Brigham and Women’s Hospital combined program in Neurology. She returned to UCSF in 2003 as a fellow in NeuroHIV with Dr. Richard Price, remaining at UCSF until moving to Yale University in 2010 where she is currently the Gilbert H. Glaser Professor of Neurology. She is active in the AIDS Clinical Trials Group, recently serving as Chair of the Neurology Collaborative Science Group and as a member of the HIV Cure committee. She has collaborated with the co-directors and other INHCC investigators in SEARCH-based studies since 2010. In addition to her research, Dr. Spudich cares for people living with HIV with neurological disorders at the Nathan Smith HIV Clinic at Yale.
Dr. Spudich is a neurologist whose clinical and translational research is focused on the pathogenesis of HIV in the nervous system, in particular the impact of acute HIV infection and early treatment on the central nervous system and the establishment of persistent CNS reservoirs for HIV. Dr. Spudich graduated from medical school at the University of California, San Francisco in 1997, then pursued residency training at the University of Washington in Internal Medicine and at the Massachusetts General Hospital/Brigham and Women’s Hospital combined program in Neurology. She returned to UCSF in 2003 as a fellow in NeuroHIV with Dr. Richard Price, remaining at UCSF until moving to Yale University in 2010 where she is currently the Gilbert H. Glaser Professor of Neurology. She is active in the AIDS Clinical Trials Group, recently serving as Chair of the Neurology Collaborative Science Group and as a member of the HIV Cure committee. She has collaborated with the co-directors and other INHCC investigators in SEARCH-based studies since 2010. In addition to her research, Dr. Spudich cares for people living with HIV with neurological disorders at the Nathan Smith HIV Clinic at Yale.
Denise Hsu, BSc (Med) MBBS, PhD
Dr. Denise Hsu is Associate Director for Therapeutics Research at US Military HIV Research Program (MHRP). Prior to her current role, Dr Hsu was a research physician under the Henry M. Jackson Foundation (HJF), in support of the U.S. Military HIV Research Program (MHRP), based at the Armed Forces Research Institute of Medical Sciences (AFRIMS) in Bangkok, Thailand. Dr. Hsu received her medical degree and PhD from the University of New South Wales, Australia. She trained in internal medicine and completed fellowships in Clinical Immunology and Allergy, and Immunopathology at the Sydney South West Area Health Network, Australia. She completed her post-doctoral fellowship on mycobacterial immune reconstitution inflammatory syndrome and immune activation in HIV infection with Dr. Irini Sereti at the National Institute of Allergy and Infectious Diseases (NIAID). Her interests include delineating the sources of HIV persistence, assessing various HIV cure interventions as well as investigating the impact of HIV on the central nervous system.
Dr. Denise Hsu is Associate Director for Therapeutics Research at US Military HIV Research Program (MHRP). Prior to her current role, Dr Hsu was a research physician under the Henry M. Jackson Foundation (HJF), in support of the U.S. Military HIV Research Program (MHRP), based at the Armed Forces Research Institute of Medical Sciences (AFRIMS) in Bangkok, Thailand. Dr. Hsu received her medical degree and PhD from the University of New South Wales, Australia. She trained in internal medicine and completed fellowships in Clinical Immunology and Allergy, and Immunopathology at the Sydney South West Area Health Network, Australia. She completed her post-doctoral fellowship on mycobacterial immune reconstitution inflammatory syndrome and immune activation in HIV infection with Dr. Irini Sereti at the National Institute of Allergy and Infectious Diseases (NIAID). Her interests include delineating the sources of HIV persistence, assessing various HIV cure interventions as well as investigating the impact of HIV on the central nervous system.
