The NeuroHIV Cure Consortium runs multiple ongoing research projects in Thailand and Africa investigating HIV in the CNS. The ultimate goal of all our research is to find a cure for HIV. Current project goals include:
- Determining if unique founder viruses are established in the central nervous system (CNS). Determine if and when viral divergence occurs in the CNS.
- Determining the CNS safety and tolerability profile of multiple proposed cure interventions, including those that include treatment interruption.
- Determining CNS-specific factors that predict success of interventions related to the CNS.
- Determining if the CNS can serve as a seed for subsequent resurgence of virus in plasma and failure of functional cure strategies.
- Determining the immediate and long-term cognitive and behavioral impact of acute HIV infection by monitoring a group before and after infection and initiation of treatment.
- Investigating behavioral factors that influence willingness to participate in cure strategies.
- Determining if early treatment during acute infection protects the CNS in the long-term.